To escape the draining Thanksgiving season with family, roommates Alyssa and John decide to throw a large friendsgiving party for their fellow Philly comics. However, Alyssa's overbearing perfectionism clashes with John's go-with-the-flow attitude, and the two spar over the elaborate plans Alyssa rushes to complete in time. John nevertheless invites the crowd over hours early, overwhelming Alyssa, still amidst the throes of adorning cupcakes with figurines and rehearsing a lengthy history lecture on the Lenape people. Ultimately kicked out until the party is ‘ready,’ John and all of their friends head to the local bar, where he starts a competing party of his own, in the form of an impromptu standup show.

Phriendsgiving is a television-style comedy, with featured sketches and standup acts peppered seamlessly throughout the overarching storyline. The featured sketch writers, teams, and comedians are all Philadelphia-based and together represent the wide variety of comedic voices and styles Philly has to offer.